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Yoda 1
CAS No. 448947-81-7
Yoda 1 ( —— )
产品货号. M20782 CAS No. 448947-81-7
Yoda1 是一种 Piezo1 离子通道激动剂(对于小鼠和人 Piezo1 转染的 HEK293T 细胞,EC50 分别 = 17.1 和 26.6 μM)。
纯度: >98% (HPLC)
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规格 | 价格/人民币 | 库存 | 数量 |
2MG | ¥446 | 有现货 |
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5MG | ¥705 | 有现货 |
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10MG | ¥948 | 有现货 |
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25MG | ¥1968 | 有现货 |
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50MG | ¥3807 | 有现货 |
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100MG | ¥5581 | 有现货 |
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500MG | ¥11826 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Yoda 1
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Yoda1 是一种 Piezo1 离子通道激动剂(对于小鼠和人 Piezo1 转染的 HEK293T 细胞,EC50 分别 = 17.1 和 26.6 μM)。
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产品描述Yoda1 is a Piezo1 ion channel agonist (EC50s = 17.1 and 26.6 μM for murine and human Piezo1-transfected HEK293T cells respectively).
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体外实验Western Blot Analysis Cell Line:human coronary artery endothelial cells (HCAECs), A431 cellsConcentration:0, 1.5, 3.0, and 6.0?μM Incubation Time:5 min Result:Induced the activation of both Akt and ERK1/2, and increased the phosphorylation levels of both Akt and ERK1/2 in a dose-dependent manner. Inhibited EGF-induced increase in the amount of Rac1-GTP, and inhibited Rac1 activation
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体Piezo1
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研究领域——
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适应症——
化学信息
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CAS Number448947-81-7
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分子量355.27
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分子式C13H8Cl2N4S2
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纯度>98% (HPLC)
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溶解度DMSO:34 mg/mL (95.70 mM)
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SMILESClc1cccc(Cl)c1CSc1nnc(-c2cnccn2)s1
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化学全称2-[5-(26-Dichloro-benzylsulfanyl)-[134]thiadiazol-2-yl]-pyrazine
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Ruhma S Jie X Dubin A E et al. Chemical activation of the mechanotransduction channel Piezo1[J]. eLife 2015 4.
产品手册
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